Arthritis after frostbite injury in children

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Reducing Amputation Rates After Severe Frostbite.

Evidence-Based Answer In patients with severe frostbite, tPA plus a prostacyclin may be used to decrease the risk of digital amputation. (Strength of Recommendation [SOR]: B, based on a single randomized controlled trial [RCT].) tPA can be used alone and is associated with lower amputation rates compared with local wound care. (SOR: C, based on lower-quality cohort studies.) A 2011, open-label ...

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ژورنال

عنوان ژورنال: Arthritis & Rheumatism

سال: 1979

ISSN: 0004-3591,1529-0131

DOI: 10.1002/art.1780221006